Two Human Monoclonal Antibodies Reacting with the Major Gangliosides of Human Melanomas and Comparison with Corresponding Mouse Monoclonal Antibodies1


The fine specificity analysis of two human monoclonal antibodies (AbFCMl and Ahi UM I ) reacting with gangliosides is described and their specificities are compared with analogous mouse monoclonal anti bodies (mAt)s). These two antibodies were generated from lymphocytes of melanoma patients by Epstein-Barr virus transformation followed by fusion with mouse… (More)


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