Two Faces of TGF-Beta1 in Breast Cancer

  title={Two Faces of TGF-Beta1 in Breast Cancer},
  author={Joanna Magdalena Zarzynska},
  booktitle={Mediators of inflammation},
Breast cancer (BC) is potentially life-threatening malignancy that still causes high mortality among women. Scientific research in this field is focused on deeper understanding of pathogenesis and progressing of BC, in order to develop relevant diagnosis and improve therapeutic treatment. Multifunctional cytokine TGF- β 1 is one of many factors that have a direct influence on BC pathophysiology. Expression of TGF- β 1, induction of canonical and noncanonical signaling pathways, and mutations in… CONTINUE READING