Two Effective Routes for Removing Lineage Restriction Roadblocks: From Somatic Cells to Hepatocytes

@inproceedings{Hu2015TwoER,
  title={Two Effective Routes for Removing Lineage Restriction Roadblocks: From Somatic Cells to Hepatocytes},
  author={Chenxia Hu and Lanjuan Li and Wenbin Deng},
  booktitle={International journal of molecular sciences},
  year={2015}
}
The conversion of somatic cells to hepatocytes has fundamentally re-shaped traditional concepts regarding the limited resources for hepatocyte therapy. With the various induced pluripotent stem cell (iPSC) generation routes, most somatic cells can be effectively directed to functional stem cells, and this strategy will supply enough pluripotent material to generate promising functional hepatocytes. However, the major challenges and potential applications of reprogrammed hepatocytes remain under… CONTINUE READING

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