Two Doses of Tranexamic Acid Reduce Blood Transfusion in Complex Spine Surgery: A Prospective Randomized Study.

@article{Raksakietisak2015TwoDO,
  title={Two Doses of Tranexamic Acid Reduce Blood Transfusion in Complex Spine Surgery: A Prospective Randomized Study.},
  author={Manee Raksakietisak and Benjabhorn Sathitkarnmanee and Peeranat Srisaen and Tithiganya Duangrat and Thitima Chinachoti and Pranee Rushatamukayanunt and Nuchanat Sakulpacharoen},
  journal={Spine},
  year={2015},
  volume={40 24},
  pages={E1257-63}
}
STUDY DESIGN Prospective, double-blinded, randomized controlled study. OBJECTIVE To determine whether the use of 2 doses of tranexamic acid (TXA) can reduce perioperative blood loss and blood transfusions in low-risk adult patients undergoing complex laminectomy. SUMMARY OF BACKGROUND DATA Complex laminectomy (multilevel laminectomy or laminectomy and instrumentation) is a procedure with a medium risk of blood loss, which may require allogeneic blood transfusion. Previous studies of TXA… CONTINUE READING
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