Two Classes of Translational Control RNA : Their Role in the Regulation of Protein Synthesis

@inproceedings{BesterTwoCO,
  title={Two Classes of Translational Control RNA : Their Role in the Regulation of Protein Synthesis},
  author={Andr{\'e} J. Bester and D S Kennedy and S M Heywood}
}
Two classes of translational control RNA (tcRNA) have been isolated from embryonic chick muscle. One of these classes, the tcRNA isolated from messenger ribonucleoprotein particles (mRNP-tcRNA), is effective in inhibiting the translation of mRNP-mRNA while having little if any effect on polysomal mRNA. The other class, polysome-tcRNA, has no effect on mRNP-mRNA while it stimulates the translation of polysomal mRNA. The mRNP-tcRNA contains approximately 50% uridylate residues and forms small but… CONTINUE READING