Two's company, three's a crowd: can H2S be the third endogenous gaseous transmitter?

  title={Two's company, three's a crowd: can H2S be the third endogenous gaseous transmitter?},
  author={Rui Wang},
  journal={The FASEB Journal},
  pages={1792 - 1798}
  • Rui Wang
  • Published 1 November 2002
  • Biology
  • The FASEB Journal
Bearing the public image of a deadly “gas of rotten eggs,” hydrogen sulfide (H2S) can be generated in many types of mammalian cells. Functionally, H2S has been implicated in the induction of hippocampal long‐term potentiation, brain development, and blood pressure regulation. By acting specifically on KATP channels, H2S can hyperpolarize cell membranes, relax smooth muscle cells, or decrease neuronal excitability. The endogenous metabolism and physiological functions of H2S position this gas… 

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