Twin study of symptom dimensions in psychoses.

  title={Twin study of symptom dimensions in psychoses.},
  author={Alastair G Cardno and Pak C. Sham and Robin MacGregor Murray and Peter McGuffin},
  journal={The British journal of psychiatry : the journal of mental science},
BACKGROUND Symptomatology in psychoses can be summarised as quantitative symptom dimensions, but their genetic basis is unknown. AIMS To investigate whether genes make an important contribution to symptom dimensions. METHOD A total of 224 probandwise twin pairs (106 monozygotic, 118 same-gender dizygotic) where probands had psychosis were ascertained from the Maudsley Twin Register in London. Factor analysis was performed on lifetime symptoms rated on the Operational Checklist for Psychotic… CONTINUE READING

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