Twin Peaks Spitz and Argos Star in Patterning of the Drosophila Egg

@article{Stevens1998TwinPS,
  title={Twin Peaks Spitz and Argos Star in Patterning of the Drosophila Egg},
  author={Leslie Stevens},
  journal={Cell},
  year={1998},
  volume={95},
  pages={291-294}
}
EGFR signaling is Argos, a secreted protein that contains an EGF repeat but which acts as an inhibitor of the EGFR (Schweitzer et al., 1995a). Interestingly, argos expression is induced in response to EGFR activation, thereby initiating a negative feedback cycle to dampen Leslie Stevens Department of Developmental and Molecular Biology Albert Einstein College of Medicine 1300 Morris Park Avenue signaling (Golembo et al., 1996b). Bronx, New York 10461 EGFR Signaling during Oogenesis The… CONTINUE READING
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