Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer.

@article{Fisher2002TwentyyearFO,
  title={Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer.},
  author={Bernard Fisher and Stewart Anderson and John Bryant and Richard G. Margolese and Melvin M Deutsch and Edwin R. Fisher and J Jeong and Norman Wolmark},
  journal={The New England journal of medicine},
  year={2002},
  volume={347 16},
  pages={1233-41}
}
BACKGROUND In 1976, we initiated a randomized trial to determine whether lumpectomy with or without radiation therapy was as effective as total mastectomy for the treatment of invasive breast cancer. METHODS A total of 1851 women for whom follow-up data were available and nodal status was known underwent randomly assigned treatment consisting of total mastectomy, lumpectomy alone, or lumpectomy and breast irradiation. Kaplan-Meier and cumulative-incidence estimates of the outcome were… CONTINUE READING
Highly Influential
This paper has highly influenced 87 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 1,713 extracted citations

Radiation therapy in the management of breast cancer.

The Surgical clinics of North America • 2013
View 7 Excerpts
Highly Influenced

New standards of care in the management of the axilla.

Current opinion in oncology • 2012
View 6 Excerpts
Highly Influenced

Triple-Negative Breast Cancer

Springer International Publishing • 2018
View 6 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…