Twenty-four hour prophylaxis with increased dosage of octreotide reduces the incidence of post-ERCP pancreatitis.

@article{Thomopoulos2006TwentyfourHP,
  title={Twenty-four hour prophylaxis with increased dosage of octreotide reduces the incidence of post-ERCP pancreatitis.},
  author={Konstantinos C. Thomopoulos and Niki A Pagoni and Konstantinos A Vagenas and Vassilios G. Margaritis and George I Theocharis and Vassiliki N. Nikolopoulou},
  journal={Gastrointestinal endoscopy},
  year={2006},
  volume={64 5},
  pages={726-31}
}
BACKGROUND Acute pancreatitis is a common complication of ERCP, occurring in up to 10% of cases. Chemoprevention of post-ERCP pancreatitis remains a debated issue. OBJECTIVE This study evaluated whether increased dosage of octreotide, a potent inhibitor of pancreatic secretion, could reduce the incidence of post-ERCP pancreatitis. DESIGN In a randomized, double-blind, placebo controlled trial, the effect of 500 microg octreotide, given 3 times daily subcutaneously starting 24 hours before… CONTINUE READING
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