Twenty-four hour pressor effect of infused adrenaline in normotensive subjects: a randomized controlled double-blind cross-over study.

@article{Blankestijn1988TwentyfourHP,
  title={Twenty-four hour pressor effect of infused adrenaline in normotensive subjects: a randomized controlled double-blind cross-over study.},
  author={Peter J Blankestijn and A J Man in't veld and Joke H. M. Tulen and Anton H. van den Meiracker and Frans Boomsma and Frans H. M. Derkx and Peter Moleman and Herman J. van Eck and Paul Mulder and Steven W. J. Lamberts},
  journal={Journal of hypertension. Supplement : official journal of the International Society of Hypertension},
  year={1988},
  volume={6 4},
  pages={S562-4}
}
Stimulation of prejunctional beta 2-adrenoceptors on sympathetic nerve terminals increases vasoconstrictor nerve activity by facilitating release of noradrenaline. Therefore, man's endogenous beta 2-adrenoceptor agonist adrenaline has been implicated in the pathogenesis of hypertension. To test this hypothesis, adrenaline (15 mg/kg per min), noradrenaline… CONTINUE READING