Twenty-four-hour leptin levels respond to cumulative short-term energy imbalance and predict subsequent intake.

@article{ChinChance2000TwentyfourhourLL,
  title={Twenty-four-hour leptin levels respond to cumulative short-term energy imbalance and predict subsequent intake.},
  author={Catherine V T Chin-Chance and Kenneth S. Polonsky and Dale A. Schoeller},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2000},
  volume={85 8},
  pages={2685-91}
}
Leptin plays a vital role in the regulation of energy balance in rodent models of obesity. However, less information is available about its homeostatic role in humans. The aim of this study was to determine whether leptin serves as an indicator of short-term energy balance by measuring acute effects of small manipulations in energy intake on leptin levels in normal individuals. The 12-day study was composed of four consecutive dietary-treatment periods of 3 days each. Baseline (BASE) [100… CONTINUE READING

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