Twenty-four-hour control with latanoprost-timolol-fixed combination therapy vs latanoprost therapy.

@article{Konstas2005TwentyfourhourCW,
  title={Twenty-four-hour control with latanoprost-timolol-fixed combination therapy vs latanoprost therapy.},
  author={Anastasios G P Konstas and Kostantinos G Boboridis and Despina Tzetzi and K Kallinderis and Jessica N Jenkins and William C Stewart},
  journal={Archives of ophthalmology},
  year={2005},
  volume={123 7},
  pages={
          898-902
        }
}
OBJECTIVE To evaluate the 24-hour efficacy and safety of the latanoprost-timolol maleate-fixed combination vs latanoprost therapy in patients with primary open-angle glaucoma. METHODS A prospective, observer-masked, crossover, active-controlled, randomized comparison in which after a 6-week medicine-free period, patients were randomized to either latanoprost-timolol-fixed combination therapy or latanoprost therapy, both dosed once each evening, alone for 8 weeks. Patients were then switched… CONTINUE READING

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Ocular hypotensive effects and safety over 3 months of switching from an unfixed combination to latanoprost 0.005%/timolol maleate 0.5% fixed combination.

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