Twelve-single nucleotide polymorphism genetic risk score identifies individuals at increased risk for future atrial fibrillation and stroke.

@article{Tada2014TwelvesingleNP,
  title={Twelve-single nucleotide polymorphism genetic risk score identifies individuals at increased risk for future atrial fibrillation and stroke.},
  author={Hayato Tada and Dov Shiffman and Jan Gustav Smith and Marketa Sj{\"o}gren and Steven A Lubitz and Patrick T Ellinor and Judy Z. Louie and Joseph J. Catanese and Gunnar Engstr{\"o}m and James J. Devlin and Sekar Kathiresan and Olle Melander},
  journal={Stroke},
  year={2014},
  volume={45 10},
  pages={2856-2862}
}
BACKGROUND AND PURPOSE Atrial fibrillation (AF) is prevalent and there is a clinical need for biomarkers to identify individuals at higher risk for AF. Fixed throughout a life course and assayable early in life, genetic biomarkers may meet this need. Here, we investigate whether multiple single nucleotide polymorphisms together as an AF genetic risk score (AF-GRS) can improve prediction of one's risk for AF. METHODS In 27 471 participants of the Malmö Diet and Cancer Study, a prospective… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 48 times over the past 90 days. VIEW TWEETS
30 Citations
38 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 30 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 38 references

A Language and Environment for Statistical Computing. Vienna, Austria: R Foundation for Statistical Computing

  • R R Core Team
  • 2012
1 Excerpt

Similar Papers

Loading similar papers…