Turnover of skeletal muscle contractile proteins in glucocorticoid myopathy

@article{Sne1994TurnoverOS,
  title={Turnover of skeletal muscle contractile proteins in glucocorticoid myopathy},
  author={T. P. S{\'e}{\'e}ne},
  journal={The Journal of Steroid Biochemistry and Molecular Biology},
  year={1994},
  volume={50},
  pages={1-4}
}
  • T. Sééne
  • Published 1 July 1994
  • Medicine, Biology
  • The Journal of Steroid Biochemistry and Molecular Biology
Role of Myofibrillar Protein Catabolism in Development of Glucocorticoid Myopathy: Aging and Functional Activity Aspects
TLDR
The aim of the present short review is to assess the role of myofibrillar protein catabolism in the development of glucocorticoid-caused myopathy from aging and physical activity aspects.
EXERCISE MYOPATHY: CHANGES IN MYOFIBRILS OF FAST-TWITCH MUSCLE FIBRES
TLDR
Myofibrils in both types of fast-twitch myopathic muscle fibres are significantly thinner as the result of more intensive protein degradation, and Regeneration capacity according to the presence of satellite cells is higher in type IIA fibres than intype IIB fibres in myopathic Muscle.
The effect of glucocorticoids on the myosin heavy chain isoforms’ turnover in skeletal muscle
The effect of glucocorticoid myopathy, unloading and reloading on the skeletal muscle contractile apparatus and extracellular matrix
During three weeks of hindlimb suspension muscle mass decreased 36% (p Soleus (Sol) muscle, 17% (p tendences to decrease in plantaris (Pla) (15%) and in extensor digitorum longus (EDL) (8%) muscles.
Influence of corticosteroids on myonuclear domain size in the rat diaphragm muscle.
TLDR
MND size does not appear to be regulated during CoS-induced DIAm atrophy, and little, if any, loss of myonuclei was associated with Cos-induced atrophy of M HC2X or MHC2B DIAM fibers.
Role of Exercise Therapy in Prevention of Decline in Aging Muscle Function: Glucocorticoid Myopathy and Unloading
TLDR
The possibilities of using exercise therapy in the prevention of glucocorticoid caused myopathy and unloading in the elderly are discussed and relationships between the muscle contractile apparatus and the extracellular matrix in different types of aging muscles are described.
Review on aging, unloading and reloading: changes in skeletal muscle quantity and quality.
Relationship between extracellular matrix, contractile apparatus, muscle mass and strength in case of glucocorticoid myopathy
Fine architectonics and protein turnover rate in myofibrils of glucocorticoid caused myopathic rats
TLDR
A positive correlation was found between the area of myofibrils where myofilaments disappeared and the my ofibrillar protein degradation rate.
Glucocorticoid-induced skeletal muscle atrophy is associated with upregulation of myostatin gene expression.
TLDR
It is proposed that dexamethasone-induced muscle loss is mediated, at least in part, by the upregulation of myostatin expression through a glucocorticoid receptor-mediated pathway.
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