Turnover of plasma cholesterol in man.

  title={Turnover of plasma cholesterol in man.},
  author={Dewitt S. Goodman and R. P. Noble},
  journal={The Journal of clinical investigation},
  volume={47 2},
Cholesterol-4-(14)C was injected intravenously into a series of normal men, untreated hyperlipidemic patients, and hyperlipidemic patients being treated with cholestyramine. The specific radioactivity of plasma total cholesterol was measured during the ensuing 10 wk. 16 studies were carried out in 10 subjects. Analysis of the turnover curves of plasma cholesterol revealed that in every study the turnover of plasma cholesterol conformed to a two-pool model. Each turnover curve was analyzed in… CONTINUE READING

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