Turnover of fibrillar collagen in soft biological tissue with application to the expansion of abdominal aortic aneurysms.

@article{Martufi2012TurnoverOF,
  title={Turnover of fibrillar collagen in soft biological tissue with application to the expansion of abdominal aortic aneurysms.},
  author={Giampaolo Martufi and T. Christian Gasser},
  journal={Journal of the Royal Society, Interface},
  year={2012},
  volume={9 77},
  pages={
          3366-77
        }
}
A better understanding of the inherent properties of vascular tissue to adapt to its mechanical environment is crucial to improve the predictability of biomechanical simulations. Fibrillar collagen in the vascular wall plays a central role in tissue adaptation owing to its relatively short lifetime. Pathological alterations of collagen turnover may fail to result in homeostasis and could be responsible for abdominal aortic aneurysm (AAA) growth at later stages of the disease. For this reason… CONTINUE READING
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