Turning placenta into brain: placental mesenchymal stem cells differentiate into neurons and oligodendrocytes.

OBJECTIVE We aimed to induce neural stem (NSC) and progenitor cells (NPC) from human placental tissues. STUDY DESIGN Placental stem cells from first-trimester placental chorionic villi and term chorion were isolated. Neural differentiation was initiated with plating on collagen, retinoic acid, and/or human brain-derived neurotrophic factor and epidermal… (More)