Turning behavior induced by injections of glutamate receptor antagonists into the substantia nigra of the rat.

@article{Murer1996TurningBI,
  title={Turning behavior induced by injections of glutamate receptor antagonists into the substantia nigra of the rat.},
  author={G M Murer and K Tseng and Vladimiro J Sinay and Rosana G. Penalva and I Armando and Jorge Horacio Pazo},
  journal={Synapse},
  year={1996},
  volume={24 2},
  pages={147-55}
}
We have found recently that muscimol microinjections into the subthalamic nucleus produce contralateral turning activity [Murer and Pazo (1993) NeuroReport, 4:1219-1222]. To test the hypothesis that a reduced glutamate action on substantia nigra pars reticulata neurons mediates this turning response, we examined the effect of unilateral intranigral microinjections of the AMPA/kainate receptor antagonist 6,7-dinitro-quinoxaline-2,3-dione (DNQX) and the competitive N-methyl-D-aspartate (NMDA… CONTINUE READING