Turner Syndrome Systematic Review: Spontaneous Thelarche and Menarche Stratified by Karyotype

  title={Turner Syndrome Systematic Review: Spontaneous Thelarche and Menarche Stratified by Karyotype},
  author={Elizabeth Dabrowski and Rachel Jensen and Emilie K. Johnson and Reema Habiby and Wendy J. Brickman and Courtney Finlayson},
  journal={Hormone Research in Paediatrics},
  pages={143 - 149}
Background: Girls with Turner syndrome (TS) have a high incidence of primary ovarian insufficiency. Recent data show rates of spontaneous thelarche (ST) of 38% and spontaneous menarche (SM) of 15–16%, with higher rates in those with mosaicism. Summary: We systematically reviewed the literature for evidence regarding rates of ST and SM in TS and evaluated rates based on the type of chromosomal mosaicism. We searched MEDLINE via PubMed, Embase, and the Cochrane Database of Controlled Trials… 

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