Turn-on fluorescence sensing of nucleoside polyphosphates using a xanthene-based Zn(II) complex chemosensor.

@article{Ojida2008TurnonFS,
  title={Turn-on fluorescence sensing of nucleoside polyphosphates using a xanthene-based Zn(II) complex chemosensor.},
  author={Akio Ojida and Ippei Takashima and Takahiro Kohira and Hiroshi Nonaka and Itaru Hamachi},
  journal={Journal of the American Chemical Society},
  year={2008},
  volume={130 36},
  pages={12095-101}
}
Fluorescence sensing with small molecular chemosensors is a versatile technique for elucidation of function of various biological substances. We now report a new fluorescent chemosensor for nucleoside polyphosphates such as ATP using metal-anion coordination chemistry. The chemosensor 1-2Zn(II) is comprised of the two sites of 2,2'-dipicolylamine (Dpa)-Zn(II) as the binding motifs and xanthene as a fluorescent sensing unit for nucleoside polyphosphates. The chemosensor 1-2Zn(II) selectively… CONTINUE READING

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