Turku sugar studies. V. Final report on the effect of sucrose, fructose and xylitol diets on the caries incidence in man.

@article{Scheinin1976TurkuSS,
  title={Turku sugar studies. V. Final report on the effect of sucrose, fructose and xylitol diets on the caries incidence in man.},
  author={A. Scheinin and K. M{\"a}kinen and K. Ylitalo},
  journal={Acta odontologica Scandinavica},
  year={1976},
  volume={34 4},
  pages={
          179-216
        }
}
The purpose was to study differences in the caries increment rate as influenced by various sugars. The trial involved almost complete substitution of sucrose (S) by fructose (F) or xylitol (X) during a period of 2 years. There were no significant initial differences as to caries status between the prospective sugar groups; 35 subjects in the S-group, 38 in the F-group, and 52 in the X-group. During the entire study 10 subjects discontinued or were excluded. The clinical and radiographical… Expand
Turku sugar studies XVIII. Incidence of dental caries in relation to 1-year consumption of xylitol chewing gum.
TLDR
The results show a profound difference in the caries increment rate between the two experimental groups, which clearly indicate a therapeutic, caries inhibitory effect of xylitol. Expand
Turku sugar studies. VI. The administration of the trial and the control of the dietary regimen.
125 voluntary subjects, divided into three groups, were originally chosen to participate in a two-year trial in which the dental and general effects of the consumption of sucrose (S 35), fructose (FExpand
Collaborative WHO xylitol field studies in Hungary. I. Three-year caries activity in institutionalized children.
TLDR
It is concluded that dietary xylitol in solid sweets resulted in a lower increment of caries than obtained in the F and C groups (p less than 0.001, covariance analysis, with base-line prevalence, number of permanent teeth, and visible plaque index as covariants). Expand
Sugar, alternative sweeteners and meal frequency in relation to caries prevention: new perspectives.
TLDR
The use of chewing gum and other xylitol-containing products have resulted in defined reduction in caries and represent interesting alternatives for high-caries-risk populations. Expand
Effectiveness of Xylitol in Caries Prevention
TLDR
Xylitol is a polyol, five-carbon sugar alcohol classified as a natural sugar substitute that possesses properties that reduce the levels of Streptococcus mutans bacteria in the dental plaque and saliva due to the disruption of the energy production process leading to bacterial cell death, adhesion reduction to the teeth and less lactic acid production. Expand
Quantification of incipient approximal caries during fructose and sucrose consumption.
  • M. Rekola
  • Medicine
  • Acta odontologica Scandinavica
  • 1989
TLDR
It is concluded that a fructose diet enhances the progression of carious lesions as much as a sucrose diet. Expand
Turku sugar studies XII. The effect of the diet on oral peroxidases, redox potential and the concentration of ionized fluorine, iodine and thiocyanate.
TLDR
It is evident that various sugars selectively affect the enzyme and other production of the salivary glands and the cariostatic properties of xylitol may partly be interrelated phenomena due to the antibacterial properties of lactoperoxidase. Expand
Collaborative WHO xylitol field studies in Hungary. II. General background and control of the dietary regimen.
The consumption of sucrose and xylitol and the exposure to fluoride (F) were analyzed in a field study aimed at assessing the value of peroral xylitol as a caries-preventive measure. The coverage ofExpand
Dietary factors in the prevention of dental caries: a systematic review
TLDR
It is suggested that the evidence for the use of sorbitol or xylitol in chewing gum, or for theuse of invert sugar, is inconclusive, and the need for well‐designed randomized clinical studies with adequate control groups and high compliance is clearly demonstrated. Expand
Turku sugar studies X. Occurrence of polysaccharide-forming streptococci and ability of the mixed plaque microbiota to ferment various carbohydrates.
TLDR
The results show a significantly lower incidence of S. mutans in the X-group relative to the S- and F-groups, and emphasize the importance of low acidogenic potential in dental plaque, generally paralleled by a low incidence of dental caries. Expand
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References

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Turku sugar studies. I. An intermediate report on the effect of sucrose, fructose and xylitol diets on the caries incidence in man.
The present report covers the results after the first year of a 2-year trial, carried out in order to evaluate eventual differences in the caries incidence as influenced by sucrose (S), fructose (F)Expand
Turku sugar studies XVIII. Incidence of dental caries in relation to 1-year consumption of xylitol chewing gum.
TLDR
The results show a profound difference in the caries increment rate between the two experimental groups, which clearly indicate a therapeutic, caries inhibitory effect of xylitol. Expand
Turku sugar studies. VI. The administration of the trial and the control of the dietary regimen.
125 voluntary subjects, divided into three groups, were originally chosen to participate in a two-year trial in which the dental and general effects of the consumption of sucrose (S 35), fructose (FExpand
Turku sugar studies X. Occurrence of polysaccharide-forming streptococci and ability of the mixed plaque microbiota to ferment various carbohydrates.
TLDR
The results show a significantly lower incidence of S. mutans in the X-group relative to the S- and F-groups, and emphasize the importance of low acidogenic potential in dental plaque, generally paralleled by a low incidence of dental caries. Expand
Turku sugar studies. VIII. Principal microbiological findings.
TLDR
It was thought that the reason for the reduction of acidogenic and aciduric oral flora in the X-group was partly due to the fact that xylitol is generally not metabolized by these microorganisms. Expand
Turku sugar studies. VII. Principal biochemical findings on whole saliva and plaque.
TLDR
The experiments indicated a selectivity of the effects of dietary carbohydrates on the biochemistry of whole saliva, plaque and salivary glands and contribute in explaining the cariostatic effects of xylitol and the lower coriogenicity of fructose when compared to sucrose. Expand
Turku sugar studies XXI. Xylitol, sorbitol-, fructose- and sucrose-induced physico-chemical changes in saliva.
TLDR
The aim was to study eventual physico-chemical changes occurring in whole saliva due to sweetened and unsweetened stimulators and found increased buffering capacity and elevation of pH saliva was found in the presence of the polyols tested. Expand
Fructose in medicine
TLDR
The apparent increase in the incidence of coronary disease among sucrose users seems to be a statistical artefact, caused by the increased ingestion of coffee and soft drinks by cigarette smokers. Expand
NMR-analysis of monomers in restorative resins.
TLDR
It was found that the BIS-GMA containing brands all contain at least one other monomer, most often TEDMA, in varying concentrations, and the brands with MMA as main component in most cases also contain other monomers. Expand
Diagnosis of Caries By Radiographic Interpretation
TLDR
A pilot study was designed to measure roughly the extent to which these or other special factors do or do not influence x-ray interpretations made for the diagnosis of dental caries. Expand
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