Tunneling Nanotubes as a Novel Route of Cell-to-Cell Spread of Herpesviruses.

@article{Panasiuk2018TunnelingNA,
  title={Tunneling Nanotubes as a Novel Route of Cell-to-Cell Spread of Herpesviruses.},
  author={Mirosława Panasiuk and Michał Rychłowski and Natalia Derewońko and Krystyna Bieńkowska-Szewczyk},
  journal={Journal of virology},
  year={2018},
  volume={92 10}
}
Various types of intercellular connections that are essential for communication between cells are often utilized by pathogens. Recently, a new type of cellular connection, consisting of long, thin, actin-rich membrane extensions named tunneling nanotubes (TNTs), has been shown to play an important role in cell-to-cell spread of HIV and influenza virus. In the present report, we show that TNTs are frequently formed by cells infected by an alphaherpesvirus, bovine herpesvirus 1 (BoHV-1). Viral… CONTINUE READING
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