Tuning the Orchestra: HCMV vs. Innate Immunity

@article{DellOste2020TuningTO,
  title={Tuning the Orchestra: HCMV vs. Innate Immunity},
  author={Valentina Dell’Oste and Matteo Biolatti and Ganna Galitska and Gloria Griffante and Francesca Gugliesi and Selina Pasquero and Alessandra Zingoni and Cristina Cerboni and Marco De Andrea},
  journal={Frontiers in Microbiology},
  year={2020},
  volume={11}
}
Understanding how the innate immune system keeps human cytomegalovirus (HCMV) in check has recently become a critical issue in light of the global clinical burden of HCMV infection in newborns and immunodeficient patients. Innate immunity constitutes the first line of host defense against HCMV as it involves a complex array of cooperating effectors – e.g., inflammatory cytokines, type I interferon (IFN-I), natural killer (NK) cells, professional antigen-presenting cells (APCs) and phagocytes… 

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