Tuning of the electronic properties of a cyclopentadienylruthenium catalyst to match racemization of electron-rich and electron-deficient alcohols.

@article{Verho2011TuningOT,
  title={Tuning of the electronic properties of a cyclopentadienylruthenium catalyst to match racemization of electron-rich and electron-deficient alcohols.},
  author={Oscar Verho and Eric V. Johnston and Erik A Karlsson and Jan-E. B{\"a}ckvall},
  journal={Chemistry},
  year={2011},
  volume={17 40},
  pages={11216-22}
}
The synthesis of a new series of cyclopentadienylruthenium catalysts with varying electronic properties and their application in racemization of secondary alcohols are described. These racemizations involve two key steps: 1) β-hydride elimination (dehydrogenation) and 2) re-addition of the hydride to the intermediate ketone. The results obtained confirm our… CONTINUE READING