Tuning core vs. shell dimensions to adjust the performance of nanoscopic containers for the loading and release of doxorubicin.

@article{Lin2011TuningCV,
  title={Tuning core vs. shell dimensions to adjust the performance of nanoscopic containers for the loading and release of doxorubicin.},
  author={Lily Yun Lin and Nam Sook Lee and Jiahua Zhu and Andreas M. Nystr{\"o}m and Darrin J. Pochan and Richard B. Dorshow and Karen L Wooley},
  journal={Journal of controlled release : official journal of the Controlled Release Society},
  year={2011},
  volume={152 1},
  pages={
          37-48
        }
}
Detailed studies were performed to probe the effects of the core and shell dimensions of amphiphilic, shell crosslinked, knedel-like polymer nanoparticles (SCKs) on the loading and release of doxorubicin (DOX), a widely-used chemotherapy agent, in aqueous buffer, as a function of the solution pH. Effects of the nanoparticle composition were held constant… CONTINUE READING