Tuning Multidomain Hemodynamic Simulations to Match Physiological Measurements

  title={Tuning Multidomain Hemodynamic Simulations to Match Physiological Measurements},
  author={Ryan L. Spilker and Charles A. Taylor},
  journal={Annals of Biomedical Engineering},
In recent years, considerable progress has been made in creating more realistic models of the cardiovascular system, often based on patient-specific anatomic data, whereas comparatively little progress has been made on incorporating measured physiological data. We have developed a method to systematically adjust the parameters of three-element windkessel outlet boundary conditions of three-dimensional blood flow models such that desired features of pressure and flow waveforms are achieved. This… CONTINUE READING


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