Tunable alignment of macromolecules by filamentous phage yields dipolar coupling interactions

@article{Hansen1998TunableAO,
  title={Tunable alignment of macromolecules by filamentous phage yields dipolar coupling interactions},
  author={Mark R. Hansen and Luciano Mueller and Arthur Pardi},
  journal={Nature Structural Biology},
  year={1998},
  volume={5},
  pages={1065-1074}
}
Dipolar coupling interactions represent an extremely valuable source of long-range distance and angle information that was previously not available for solution structure determinations of macromolecules. This is because observation of these dipolar coupling data requires creating an anisotropic environment for the macromolecule. Here we introduce a new method for generating tunable degrees of alignment of macromolecules by addition of magnetically aligned Pf1 filamentous bacteriophage as a… CONTINUE READING
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