Tumourigenic effect of Schistosoma haematobium total antigen in mammalian cells.

  title={Tumourigenic effect of Schistosoma haematobium total antigen in mammalian cells.},
  author={M{\'o}nica Catarina Botelho and Paula Alexandra Oliveira and Joana Gomes and F{\'a}tima Gartner and Carlos Frederico Costa Lopes and Jos{\'e} Manuel Correia da Costa and Jos{\'e} Carlos Machado},
  journal={International journal of experimental pathology},
  volume={90 4},
Schistosoma haematobium is endemic in several regions of Africa and has been shown to be associated with predominantly squamous cell bladder carcinoma. The mechanisms underlying the association between S. haematobium and bladder squamous cell carcinoma is largely unknown. All the reports so far, demonstrate exclusively an epidemiological evidence linking S. haematobium infection with squamous cell bladder carcinoma. We hypothesized that these parasite antigens might induce tumourigenesis. For… CONTINUE READING
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