Tumour-suppressor function in the nervous system

  title={Tumour-suppressor function in the nervous system},
  author={Suzanne J. Baker and Peter J Mckinnon},
  journal={Nature Reviews Cancer},
Tumour suppressors prevent cancer by regulating processes such as cell proliferation and survival. However, their functions are diverse, and are often related to the cell type and tissue context. Mutations of tumour-suppressor genes result in unique outcomes in the nervous system that contrast with their roles in other organs. This is closely related to the cell types in which mutations occur and the developmental stage of the tissues that are affected. How can studying the tissue-specific… CONTINUE READING