Tumour suppression: Putting on the brakes

@article{Harris2004TumourSP,
  title={Tumour suppression: Putting on the brakes},
  author={Henry Harris},
  journal={Nature},
  year={2004},
  volume={427},
  pages={201-201}
}
It is a common assumption that somatic cells do not multiply unless they are stimulated to do so, and if they do not receive the necessary external or internal stimuli they are said to remain in the ‘resting’ phase. But this assumption is far from self-evident. It is entirely plausible to regard exponential multiplication, and not repose, as the cell’s natural steady state. As a result of evolution, the cellular machinery for the conversion of nutrients into energy is geared towards cell… CONTINUE READING

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