Tumour necrosis factor-alpha up-regulates macrophage migration inhibitory factor expression in endometrial stromal cells via the nuclear transcription factor NF-kappaB.

@article{Cao2006TumourNF,
  title={Tumour necrosis factor-alpha up-regulates macrophage migration inhibitory factor expression in endometrial stromal cells via the nuclear transcription factor NF-kappaB.},
  author={W. G. Cao and Mathieu Morin and Val{\'e}rie Sengers and Christine M Metz and Thierry Roger and Rodolphe Maheux and Ali Akoum},
  journal={Human reproduction},
  year={2006},
  volume={21 2},
  pages={421-8}
}
BACKGROUND A series of controlled changes including proliferation, secretion and menstrual shedding occur in the human endometrium during every normal menstrual cycle. Macrophage migration inhibitory factor (MIF), a multifunctional cytokine with numerous proinflammatory, immunomodulatory and angiogenic properties, appears to be expressed in the human endometrium and to follow a regulated cycle phase-dependent expression, but the mechanisms underlying endometrial MIF expression remain to be… CONTINUE READING

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