Tumour necrosis factor-alpha induces Langerhans cell migration in humans.

Abstract

The role of tumour necrosis factor (TNF)-alpha in the mobilization and migration of human epidermal Langerhans cells (LC) has been investigated. Intradermal injection of normal human volunteers with homologous recombinant TNF-alpha was found to cause a dose-dependent reduction in the frequency of LC within epidermal sheets 2 h later. Equivalent results were… (More)

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@article{Cumberbatch1999TumourNF, title={Tumour necrosis factor-alpha induces Langerhans cell migration in humans.}, author={Marie Cumberbatch and C E M Griffiths and Simon C Tucker and R. J. Dearman and Ian R Kimber}, journal={The British journal of dermatology}, year={1999}, volume={141 2}, pages={192-200} }