Tumour necrosis factor-alpha enhances intraepithelial lymphocyte proliferation and migration.

Abstract

BACKGROUND Tumour necrosis factor alpha (TNF-alpha) is a proinflammatory cytokine found in abundance in diseased intestine. AIMS The T cell production of TNF-alpha and the impact of this cytokine on intestinal T cell proliferation, migration, and cytotoxicity were studied. METHODS Intestinal lymphocytes from normal jejunum were used. TNF-alpha… (More)

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