Tumour necrosis factor α and interleukin 1 signalling: do MAPKK kinases connect it all?

@inproceedings{Eder1997TumourNF,
  title={Tumour necrosis factor α and interleukin 1 signalling: do MAPKK kinases connect it all?},
  author={Joerg Eder},
  year={1997}
}
Abstract The potent pro-inflammatory cytokines tumour necrosis factor α (TNF-α) and interleukin 1 (il-1) are capable of triggering biologically similar effects through activation of the same set of transcription factors. Based on recent findings it is now becoming evident that certain members of the mitogen-activated protein kinase kinase (MAPKK) kinase protein family serve to integrate the individual signal transduction pathways that are initiated by the two cytokines into an array of parallel… CONTINUE READING

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