Tumour-cell-induced production of tumour necrosis factor by monocytes of gastric cancer patients receiving BCG immunotherapy

Abstract

Human peripheral blood monocytes cocultured with tumour cells were used as an in vitro model of in situ interactions between tumour-infiltrating macrophages and the tumour. Tumour cells stimulated de novo expression of the human tumour necrosis factor α (TNF) gene in monocytes and caused the release of TNF into the culture supernatant. A group of 14… (More)
DOI: 10.1007/BF01754413

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@article{Zembala1993TumourcellinducedPO, title={Tumour-cell-induced production of tumour necrosis factor by monocytes of gastric cancer patients receiving BCG immunotherapy}, author={Marek Zembala and Antoni Czupryna and Jerzy Więckiewicz and Marek Jasinski and Juliusz R Pryjma and Irena Ruggiero and Maciej Siedlar and Tadeusz J. Popiela}, journal={Cancer Immunology, Immunotherapy}, year={1993}, volume={36}, pages={127-132} }