Tumour budding with and without admixed inflammation: two different sides of the same coin?

  title={Tumour budding with and without admixed inflammation: two different sides of the same coin?},
  author={Nicole Max and L. Harbaum and M. Pollheimer and R. Lindtner and P. Kornprat and C. Langner},
  journal={British Journal of Cancer},
  pages={368 - 371}
  • Nicole Max, L. Harbaum, +3 authors C. Langner
  • Published 2016
  • Biology, Medicine
  • British Journal of Cancer
  • Background:Tumour budding is an adverse prognostic indicator in colorectal cancer (CRC). Marked overall peritumoural inflammation has been associated with favourable outcome and may lead to the presence of isolated cancer cells due to destruction of invading cancer cell islets.Methods:We assessed the prognostic significance of tumour budding and peritumoural inflammation in a cohort of 381 patients with CRC applying univariate and multivariate analyses.Results:Patients with high-grade budding… CONTINUE READING
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