Tumour budding: a promising parameter in colorectal cancer

  title={Tumour budding: a promising parameter in colorectal cancer},
  author={Alessandro Lugli and Eva Karamitopoulou and Inti Zlobec},
  booktitle={British Journal of Cancer},
In 2011, the Tumour Node Metastasis (TNM) staging system still remains the gold standard for stratifying colorectal cancer (CRC) patients into prognostic subgroups, and is considered a solid basis for treatment management. Nevertheless, there is still a challenge with regard to therapeutic strategy; stage II patients are not typically selected for postoperative adjuvant chemotherapy, although some stage II patients have a comparable outcome to stage III patients who, themselves do receive such… CONTINUE READING
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Tumour budding score based on 10 high-power fields (HPFs) is a reliable basis for a standardized scoring system in colorectal cancer

  • V Koelzer, M Horcic, LM Terracciano, I Zlobec, A Lugli
  • Virchows Archiv
  • 2011
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