Tumorous variant of scleromyxedema. Successful therapy with intravenous immunoglobulins.

@article{WojasPelc2005TumorousVO,
  title={Tumorous variant of scleromyxedema. Successful therapy with intravenous immunoglobulins.},
  author={Anna Wojas-Pelc and Maria Błaszczyk and M. Glinska and Stefania Jabłońska},
  journal={Journal of the European Academy of Dermatology and Venereology : JEADV},
  year={2005},
  volume={19 4},
  pages={462-5}
}
We present an unusual tumorous variety of scleromyxedema mimicking facies leonina in lymphoma. In spite of pronounced and widespread cutaneous changes, hypergammaglobulinaemia and paraproteinaemia, the general condition of the patient was satisfactory, there was no internal involvement and no symptoms of any malignancy. Initially, melphalan and corticosteroids were applied but were not effective. High-dose intravenous immunoglobulin (IVIG) therapy had dramatic effect, and after five 5-day… CONTINUE READING

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