Tumorigenicity of the dihydrodiols of dibenzo(a,h)anthracene on mouse skin and in newborn mice.

Abstract

INTRODUCTION Dibenzo(a,h)anthnacene and the three metabolically pos sible trans-dihydrodiols of dibenzo(a,h)anthracene were tested for tumorigenic activity on mouse skin and in new born mice. in the tumorigenicity study on mouse skin, a single topical application of 10 to 160 nmol of compound was followed 7 days later by twice-weekly applications of the… (More)

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