Tumorigenesis and metastasis of neoplastic Kaposi's sarcoma cell line in immunodeficient mice blocked by a human pregnancy hormone

@article{Lunardilskandar1995TumorigenesisAM,
  title={Tumorigenesis and metastasis of neoplastic Kaposi's sarcoma cell line in immunodeficient mice blocked by a human pregnancy hormone},
  author={Yanto Lunardi-lskandar and Joseph L. Bryant and Robert Zeman and Victor H. Lam and Felipe Samaniego and Jacques M. Besnier and Philippe Hermans and Alain R. Thierry and Parkash Gill and Robert C. Gallo},
  journal={Nature},
  year={1995},
  volume={375},
  pages={64-68}
}
KAPOSI'S sarcoma (KS) occurs more often in men than in women and HIV-l-associated KS has a high occurrence in homosexual men (over 30%). Most cultures of KS tumours yield cells with properties of hyperplastic (not malignant) endothelial cells under the control of several cytokines1á\[euro]-7. The role of HIV-1 may be in promoting high levels of some cytokines and providing stimulation to angiogenesis by the HIV-1 Tat protein8, which synergizes with basic fibroblast growth factor in promoting… CONTINUE READING

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