Tumorigenesis: Cell Defense Against Hypoxia?

@inproceedings{Pakravan2013TumorigenesisCD,
  title={Tumorigenesis: Cell Defense Against Hypoxia?},
  author={Nafiseh Pakravan},
  booktitle={Oncology reviews},
  year={2013}
}
Microenvironmental elements can directly contribute to the induction and the maintenance of tumor. Oxygen is the main element in the cell microenvironment and hypoxia can affect the process of tumorigenesis. In response to hypoxia, cells change their pattern and characteristics. These changes suggest that it is not just adaptation, but some sort of cell defense against hypoxia. If hypoxia is corrected, then cell defense mechanisms are interrupted. An examination of the process of tumorigenesis… CONTINUE READING

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