Tumoral mast cells exhibit a common spatial distribution.


Mast cells (MCs) accumulate in the stroma surrounding tumors and take part in the inflammatory reaction occurring at the margin of the neoplasia. Moreover, MC secretes angiogenic cytokines and matrix metalloproteinases. The aim of this study was to investigate the pattern of distribution of MCs in biopsy samples obtained from four different human tumors… (More)
DOI: 10.1016/j.canlet.2008.07.032