Tumor vascularity--a novel prognostic factor in advanced cervical carcinoma.

  title={Tumor vascularity--a novel prognostic factor in advanced cervical carcinoma.},
  author={Karlheinz Schlenger and Michael H{\"o}ckel and Margarete Mitze and Utz Sch{\"a}ffer and Wolfgang Weikel and Paul Georg Knapstein and Ann Lambert},
  journal={Gynecologic oncology},
  volume={59 1},
OBJECTIVE In the search for the optimal treatment of advanced cervical cancer, the identification of valid prognostic factors obtainable without histopathologic investigation of the entire tumor and the locoregional lymph nodes is of paramount interest. Tumor microvessel density has recently been demonstrated to correlate strongly with disease aggressiveness in breast cancer and other malignancies. METHODS We established a computerized image analysis system to quantify tumor microvascularity… CONTINUE READING


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