Tumor vaccines--application to childhood cancer.

  title={Tumor vaccines--application to childhood cancer.},
  author={M A Roskrow and Andree Zibert and Manfred Souquet and Dagmar Dilloo},
  journal={Klinische Padiatrie},
  volume={211 4},
Currently, several clinical studies explore the therapeutic potential of tumor vaccines which are genetically modified to produce immunostimulatory molecules as a complementary approach for conventional cancer therapy. In this review the immunological basis and the preclinical design of such vaccine strategies are described with particular emphasis to acute… CONTINUE READING