Tumor targeting with antibody-functionalized, radiolabeled carbon nanotubes.

  title={Tumor targeting with antibody-functionalized, radiolabeled carbon nanotubes.},
  author={Michael R McDevitt and Debjit Chattopadhyay and Barry J. Kappel and Jaspreet Singh Jaggi and Scott R Schiffman and Christophe Antczak and Jon T Njardarson and Renier J. Brentjens and David A. Scheinberg},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  volume={48 7},
UNLABELLED Single-walled carbon nanotubes (CNT) are mechanically robust graphene cylinders with a high aspect ratio that are comprised of sp(2)-bonded carbon atoms and possessing highly regular structures with defined periodicity. CNT exhibit unique mechanochemical properties that can be exploited for the development of novel drug delivery platforms. We hypothesized that novel prototype nanostructures consisting of biologics, radionuclides, fluorochromes, and CNT could be synthesized and… CONTINUE READING
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