Tumor-targeted nanomedicines for cancer theranostics.

  title={Tumor-targeted nanomedicines for cancer theranostics.},
  author={Alexandra G Arranja and Vertika Pathak and Twan Lammers and Yang Shi},
  journal={Pharmacological research},
Chemotherapeutic drugs have multiple drawbacks, including severe side effects and suboptimal therapeutic efficacy. Nanomedicines assist in improving the biodistribution and target accumulation of chemotherapeutic drugs, and are therefore able to enhance the balance between efficacy and toxicity. Multiple types of nanomedicines have been evaluated over the years, including liposomes, polymer-drug conjugates and polymeric micelles, which rely on strategies such as passive targeting, active… CONTINUE READING