Tumor suppressor genes associated with drug resistance in ovarian cancer (review).

@article{Yin2013TumorSG,
  title={Tumor suppressor genes associated with drug resistance in ovarian cancer (review).},
  author={Fuqiang Yin and Xia Liu and Danrong Li and Qi Wang and Wei Zhang and Li Li},
  journal={Oncology reports},
  year={2013},
  volume={30 1},
  pages={3-10}
}
Ovarian cancer is a fatal gynecological cancer and a major cause of cancer-related mortality worldwide. The main limitation to a successful treatment for ovarian cancer is the development of drug resistance to combined chemotherapy. Tumor suppressor genes (TSGs) are wild-type alleles of genes which play regulatory roles in diverse cellular activities, and whose loss of function contributes to the development of cancer. It has been demonstrated that TSGs contribute to drug resistance in several… CONTINUE READING
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