Tumor suppressor genes and related molecules in leiomyosarcoma.

  title={Tumor suppressor genes and related molecules in leiomyosarcoma.},
  author={Angelo P Dei Tos and Roberta Maestro and Claudio Doglioni and Sara Piccinin and Duilio Della Libera and Mauro Boiocchi and Christopher D. M. Fletcher},
  journal={The American journal of pathology},
  volume={148 4},
Soft tissue sarcomas represent a heterogeneous group of mesenchymal malignancies, and the majority of the previous scientific studies that have analyzed the occurrence of cell cycle regulators aberrations within soft tissue sarcomas have dealt with broad categories of different tumors. As a consequence, data concerning single classes of sarcomas are very limited. The authors analyze herein a histologically homogeneous series of 23 cases of leiomyosarcoma of the deep soft tissue. The p53 pathway… CONTINUE READING


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