Tumor suppressor genes and medulloblastoma

@article{Cogen1996TumorSG,
  title={Tumor suppressor genes and medulloblastoma},
  author={Philip H. Cogen and Jeffrey D. McDonald},
  journal={Journal of Neuro-Oncology},
  year={1996},
  volume={29},
  pages={103-112}
}
Although primary intracranial neoplasms are the most common type of solid cancer in children, little is known about their etiology at the molecular genetic level. Recently, studies have shown that a class of genes known as tumor suppressors play an important role in the origin of several different types of human tumors, including those located in the central nervous system (CNS). Using a variety of techniques, selective loss of DNA sequences has been identified in tissue specimens from children… CONTINUE READING

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